Rejuran Guide: What It Is, What It Helps With, and How the Course Works

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Updated on September 29, 2026

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Rejuran Guide: What It Is, What It Helps With, and How the Course Works

Rejuran is a group of injectable products discussed for wrinkles, skin texture, elasticity or firmness, and overall skin quality. The protocol is one injection per month for three consecutive months; 2 cc is used for a specific area and 4 cc for the whole face. A clinician should assess the area and explain the plan before treatment.

Quick summary

  • Rejuran is discussed in the context of wrinkles, texture, elasticity or firmness, and overall skin quality.
  • The course is one treatment each month for three consecutive months.
  • The stated framework is 2 cc for a specific area and 4 cc for the whole face; a 2 cc whole-face distribution must be discussed with the clinician, with the outcome accepted as explained.
  • After the completed course, the duration may be 6–8 months.
  • Vitaran/Rejuran maintenance may continue once a month according to the patient’s needs, after discussion with a clinician.
  • Health history and current medicines should be disclosed before treatment, and the treated area should be handled gently afterward.

Read the section that fits your question

<h2 id=”rejuran-what-is”>What is Rejuran?</h2>

Rejuran is a name used for a group of injectable products discussed for wrinkles and overall skin quality. The treatment is described in relation to Layer 3, or the reticular dermis, a deeper dermal layer associated with collagen and elastin structure and with skin elasticity and firmness as skin ages.

The decision about treatment area, volume, and plan should begin with the person’s goals and a clinician’s assessment. The protocol values in this guide are not a substitute for an individual treatment decision.

<h2 id=”rejuran-helps-with”>What does Rejuran help with?</h2>

People may consider Rejuran in relation to:

  • Facial wrinkles
  • Uneven-looking skin texture
  • Skin elasticity or firmness
  • Overall skin quality

These are treatment goals, not a guarantee of a particular result. The relevant area and plan depend on the assessment and the goal being discussed.

<h2 id=”rejuran-who”>Who may be considering Rejuran?</h2>

Rejuran may be considered by people whose goals involve wrinkles or overall skin quality and who are prepared to discuss the area, volume, and plan with a clinician before deciding.

Before treatment, disclose relevant health information and current medicines. Disclose infection or inflammation at the intended area, allergies, pregnancy or breastfeeding, medical conditions, and medicines that may increase bleeding. Do not stop regular medicine without advice from the prescriber.

<h2 id=”rejuran-course-volume”>How many sessions and how many cc?</h2>

The course is one treatment per month for three consecutive months. The volume framework is:

  • Specific area: 2 cc may be used for a specific area.
  • Whole face: 4 cc is stated for the whole face.
  • 2 cc distributed across the whole face: discuss this with the clinician and accept the outcome as the clinician explains it.

The volume and distribution should be explained before treatment. Personal planning adds an assessment step; it does not replace the protocol framework above or create new values.

<h2 id=”rejuran-maintenance”>How long may the result last and what comes next?</h2>

After the completed protocol, the duration is 6–8 months. Vitaran/Rejuran may be maintained once a month according to the patient’s needs.

Use these points as questions for a clinician rather than as an automatic schedule for every person. Any ongoing plan should be discussed in relation to the treatment goal and the person’s assessment.

<h2 id=”rejuran-safety”>What should you check before and after treatment?</h2>

Before treatment, explain allergies, pregnancy or breastfeeding, medical conditions, infection or inflammation at the intended area, and medicines or supplements being used. Ask the clinician to explain the area, goal, volume, and follow-up before deciding.

After treatment, follow the clinic’s instructions and handle the injection area gently. Avoid pressing, massaging, picking, or squeezing it. Use gentle products as advised and avoid heat, friction, or other irritants according to the instructions you receive. Do not add medicines, creams, or supplements yourself, and do not stop regular medication without speaking with the prescriber.

If the injection-area symptoms worsen rapidly or you have difficulty breathing, seek emergency medical care immediately. For routine aftercare questions, use the follow-up channel provided to you.

A practical consultation checklist

Before a discussion, note your main skin goal, the area that concerns you, your health history, allergies, and current medicines or supplements. Ask which volume applies to the intended area, how the distribution will be explained, and what follow-up instructions you should receive. The clinician’s assessment should clarify the plan before treatment.

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<h2 id=”faq”>Frequently asked questions</h2>

<div class=”oy-faq”>
<div class=”oy-faq__row”>
<div class=”oy-faqquestion”><span class=”oy-faqbadge” aria-hidden=”true”>1</span><h3>What is Rejuran?</h3></div>
<p>Rejuran is a group of injectable products discussed for wrinkles and overall skin quality, with the area and plan decided after a clinician’s assessment.</p>
<div class=”oy-faq__divider” aria-hidden=”true”></div>
</div>
<div class=”oy-faq__row”>
<div class=”oy-faqquestion”><span class=”oy-faqbadge” aria-hidden=”true”>2</span><h3>What is the Rejuran course?</h3></div>
<p>The course is one treatment per month for three consecutive months.</p>
<div class=”oy-faq__divider” aria-hidden=”true”></div>
</div>
<div class=”oy-faq__row”>
<div class=”oy-faqquestion”><span class=”oy-faqbadge” aria-hidden=”true”>3</span><h3>How many cc are used?</h3></div>
<p>The stated framework is 2 cc for a specific area and 4 cc for the whole face. If 2 cc is to be distributed across the whole face, discuss it with the clinician and understand the outcome explained before treatment.</p>
<div class=”oy-faq__divider” aria-hidden=”true”></div>
</div>
<div class=”oy-faq__row”>
<div class=”oy-faqquestion”><span class=”oy-faqbadge” aria-hidden=”true”>4</span><h3>How long does the completed protocol last?</h3></div>
<p>The duration may be 6–8 months after the completed protocol. Vitaran/Rejuran may be maintained once a month according to the patient’s needs, after discussion with a clinician.</p>
<div class=”oy-faq__divider” aria-hidden=”true”></div>
</div>
<div class=”oy-faq__row”>
<div class=”oy-faqquestion”><span class=”oy-faqbadge” aria-hidden=”true”>5</span><h3>What should you do after Rejuran?</h3></div>
<p>Follow the instructions provided to you, handle the injection area gently, and avoid pressing, massaging, picking, or squeezing it. Seek emergency care for rapidly worsening injection-area symptoms or difficulty breathing.</p>
</div>
</div>

<p><strong>CTA:</strong> If you are considering Rejuran, prepare your goals, intended area, health history, and current medicines for a discussion with an appropriate clinician before deciding.</p>

This article was medically reviewed by

Mr. Park Young Jin

Education

Graduated with a Doctor of Medicine degree from Inha University College of Medicine, and completed an executive program at Seoul National University. Gained experience as a Public Doctor within the government sector before advancing into Aesthetic Medicine with leading Korean clinic groups, including Forever Plastic Surgery, Ppeum Clinic, and Y&I Clinic, serving as a physician and Senior Doctor

Specializes in

Specializes in Aesthetic Medicine, Facial Contouring, and Facelifting Techniques, serving as President of the Obliv Clinic Network (Incheon, Bangkok, Dubai). Also active in the academic community as Academy Director of the Korean Aesthetic Surgery & Laser Society and Senior Director of the Korean Academy of Facelifting and Contouring , as well as a Global KOL and Key Doctor for leading brands including Wontech, MERZ, Jetema, Amalian, and Gouri, covering Filler, Energy-Based Devices, and Skin Rejuvenation technologies internationally. Source: Aestheticsa